Polynucleotide Skin Regeneration at AesClinica Harley Street London
At AesClinica London, we’re proud to offer the latest Polynucleotide skin rejuvenation treatment an advanced injectable therapy designed to repair, regenerate, and revitalise your skin at a cellular level.
Located in the heart of Harley Street, our clinic specialises in non-surgical aesthetic treatments that restore your skin’s youth, elasticity, and radiance naturally without fillers or toxins.
Polynucleotide Treatment
Discover the next generation of regenerative aesthetics with Polynucleotide injections at AesClinica London. This innovative skin therapy uses bio-revitalising molecules to deeply repair, hydrate, and rejuvenate your skin from within offering powerful anti-ageing results with zero downtime.
What Is Polynucleotide Skin Rejuvenation?
Polynucleotides (PNs) are biostimulatory molecules derived from natural DNA fragments. When injected into the skin, they stimulate collagen production, boost hydration, and activate tissue regeneration.
Unlike dermal fillers that simply add volume, Polynucleotides repair the skin from within, improving its structure, texture, and resilience over time.
At AesClinica Harley Street, our experts use leading products such as Plenhyage XL and Nucleofill trusted and clinically proven Polynucleotide solutions for long-lasting skin rejuvenation.
How Do Polynucleotide Injections Work?
The science behind Polynucleotides is rooted in cellular bio-regeneration. Once injected, they:
Attract water molecules, deeply hydrating the skin
Promote fibroblast activity, boosting collagen and elastin production
Repair damaged DNA within skin cells
Reduce oxidative stress, improving skin health
This leads to visibly smoother, firmer, and more radiant skin naturally and progressively.
Benefits of Polynucleotide Treatment at AesClinica London
Polynucleotide treatments are ideal for anyone looking to improve their skin’s quality and reverse early signs of ageing.
Key benefits include:
Deep skin hydration and glow ✨
Reduction in fine lines and wrinkles
Improved skin texture and elasticity
Skin tightening and lifting effects
Reduction in pigmentation and dark circles
Enhanced healing and anti-inflammatory properties
Suitable for face, neck, under-eye area, and décolletage
Performed by experts at AesClinica Harley Street, the treatment is minimally invasive with no downtime.
What to Expect During Your Polynucleotide Treatment at AesClinica Harley Street
Consultation: Our skin specialist will assess your skin condition and create a personalised plan.
Treatment: Polynucleotide injections are gently administered into targeted areas using fine needles.
Aftercare: You can return to normal activities immediately after treatment. Mild redness or swelling may appear and typically resolves within 24–48 hours.
A full course usually includes 2–3 sessions, spaced 2–4 weeks apart, for optimal results.
Bofore & After






FAQS
What are Polynucleotides?
Polynucleotides are naturally derived DNA molecules that repair and regenerate the skin at a cellular level, improving hydration, elasticity, and radiance.
Is the treatment painful?
AesClinica, located at 96 Harley Street, London W1G 7HY, is a trusted clinic offering advanced Emsculpt Neo treatments performed by expert practitioners.
How many sessions will I need?
We recommend 2–3 sessions spaced 2–4 weeks apart for the best and longest-lasting results.
When will I see results?
Visible improvement usually appears within 2–3 weeks, with continued enhancement over the next few months.
Is there any downtime?
There is little to no downtime. Mild redness or swelling may occur but typically subsides within a day.
Which areas can be treated with Polynucleotides?
Popular areas include the face, under-eyes, neck, and décolletage.
How long do results last?
Results can last 6–12 months, depending on individual skin type and maintenance.
Are Polynucleotide injections safe?
Yes Polynucleotides are biocompatible and clinically tested. All treatments at AesClinica Harley Street are performed by trained medical professionals.
Book Your Polynucleotide Consultation at AES Clinica Harley Street
Ready to rejuvenate your skin naturally?
Visit AesClinica London, located at 96 Harley Street, W1G 7HY, and discover how Polynucleotide skin regeneration can transform your complexion.
