Polynucleotide
At AesClinica, our expert aesthetic team uses medical-grade polynucleotide products tailored to your skin’s unique needs. Whether used alone or combined with microneedling or other treatments, results are natural, progressive, and long-lasting.
Polynucleotide Treatment
What are Polynucleotides?
Polynucleotides are naturally derived molecules (DNA fragments) that stimulate cell regeneration, collagen production, and tissue repair. Unlike dermal fillers, they don’t add volume — they enhance skin quality, texture, and elasticity over time.
Benefits of Polynucleotide Treatment:
Improves skin firmness and elasticity
Deeply hydrates and restores skin barrier
Reduces fine lines and crepey texture
Brightens dull, tired skin
Can be used on the face, under-eyes, neck & hands
Bofore & After






FAQS
What is polynucleotide treatment?
Polynucleotide treatment is a regenerative aesthetic therapy that uses purified DNA fragments to stimulate cell repair, improve skin quality, and promote natural collagen and elastin production. It’s ideal for ageing, dull, or dehydrated skin.
What skin concerns can polynucleotides treat?
Polynucleotides are effective for:
- Fine lines and wrinkles
- Thin or crepey skin
- Under-eye hollows and dark circles
- Dullness and poor texture
- Dehydration and inflammation
How soon will I see results from polynucleotide injections?
You may notice improved hydration and glow within 7–10 days, with firmness, elasticity, and skin texture gradually improving over 4–6 weeks. A course of treatments offers optimal results.
Is polynucleotide treatment safe?
Yes. At AesClinica London, we use CE-certified, clinically tested polynucleotide products. The treatment is biocompatible and well-tolerated, with minimal downtime or side effects.
How many sessions are needed?
We typically recommend 3 sessions spaced 2–4 weeks apart, followed by maintenance every 4–6 months, depending on your skin’s condition and goals.